Sildenafil citrate, commercially known as viagre and commonly known as Viagra, is a cyclic guanosine phosphate (cGMP) specific type 5 phosphodilipase (PDE5) inhibitor that can enhance erections when taken orally. Sildenafil citrate can enhance the action of nitric oxide (NO) by inhibiting the type 5 Chemicalbook phosphodiesterase in penile sponges which decomposes cyclic guanosine (cGMP), and increase the level of cGMP in sponges, relax the smooth muscle in sponges and increase blood inflow when NO is released locally due to sexual stimulants. The continuous erection of the penis is prolonged and the stiffness is increased. For impotence patients with penile erectile dysfunction.
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